CCL13 ELISA Kit for Human(Homo sapiens) | EIAab.comCCL13 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > CCL13(Gene name) > Human

CCL13 (Gene name),

C-C motif chemokine 13 (Protein name ), CCL13_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

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Gene name:

CCL13(MCP4;NCC1;SCYA13);

Protein name:

C-C motif chemokine 13;

Alternative:

Monocyte chemoattractant protein 4;CK-beta-10;NCC-1;Monocyte chemotactic protein 4(MCP-4);Small-inducible cytokine A13;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

N/A

Function:

Chemotactic factor that attracts monocytes, lymphocytes, basophils and eosinophils, but not neutrophils. Signals through CCR2B and CCR3 receptors. Plays a role in the accumulation of leukocytes at both sides of allergic and non-allergic inflammation. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis. May play a role in the monocyte attraction in tissues chronically exposed to exogenous pathogens.

Subcellular Location:

Secreted

Protein Attributes:

Sequence length:

Sequence:

50:

98:

YVITTSRCPQ | KAVIFRTKLG | KEICADPKEK | WVQNYMKHLG | RKAHTLKT

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Hs.414629

STRING:

9606.ENSP00000225844

Pfam:

PF00048

MIM:

601391

SMR:

Q99616

KEGG:

hsa:6357

String:

Q99616

Uniprot:

Q99616

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ELISA Kit for Human C-C motif chemokine 13

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E0216h

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Manual:

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96T

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ELISA Kit for Human C-C motif chemokine 13

Cat.:

E0216d

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Packing:

96T

CLIA Kit for Human C-C motif chemokine 13

Cat.:

U0216d

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Packing:

96T

CLIA Kit for Human C-C motif chemokine 13

Cat.:

U0216h

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Packing:

96T

Polyclonal Antibody for Human C-C motif chemokine 13

Cat.:

P0216Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human C-C motif chemokine 13

Monoclonal Antibody for Human C-C motif chemokine 13

Protein for Human C-C motif chemokine 13

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"Cloning and characterization of MCP-4, a novel CC chemokine related to MCP-1 and eotaxin."
Power C.A. , Meyer A. , Rison S.C.G. , Guye-Coulin F. , Wells T.N.C.
Eur. Cytokine Netw.7:513-513(1996)

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Lung.
2.

"Human monocyte chemoattractant protein (MCP)-4 is a novel CC chemokine with activities on monocytes, eosinophils, and basophils induced in allergic and nonallergic inflammation that signals through the CC chemokine receptors (CCR)-2 and -3."
Garcia-Zepeda E.A. , Combadiere C. , Rothenberg M.E. , Sarafi M.N. , Lavigne F. , Hamid Q. , Murphy P.M. , Luster A.D.
J. Immunol.157:5613-5626(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Heart.
3.

"Monocyte chemotactic protein 4 (MCP-4), a novel structural and functional analogue of MCP-3 and eotaxin."
Uguccioni M. , Loetscher P. , Forssmann U. , Dewald B. , Li H. , Lima S.H. , Li Y. , Kreider B. , Garotta G. , Thelen M. , Baggiolini M.
J. Exp. Med.183:2379-2384(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PROTEIN SEQUENCE OF 17-98;PYROGLUTAMATE FORMATION AT GLN-24;MASS SPECTROMETRY
tissue: Fetus.
4.

"Cloning, in vitro expression, and functional characterization of a novel human CC chemokine of the monocyte chemotactic protein (MCP) family (MCP-4) that binds and signals through the CC chemokine receptor 2B."
Berkhout T.A. , Sarau H.M. , Moores K. , White J.R. , Elshourbagy N. , Appelbaum E. , Reape T.J. , Brawner M. , Makwana J. , Foley J.J. , Schmidt D.B. , Imburgia C. , Macnulty D. , Matthews J. , O'Donnell K. , O'Shannessy D. , Scott M. , Groot P.H.E. , more...
J. Biol. Chem.272:16404-16413(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PROTEIN SEQUENCE OF 22-33;IDENTIFICATION BY MASS SPECTROMETRY
tissue: Fetus.
5.

"Monocyte chemotactic protein-4: tissue-specific expression and signaling through CC chemokine receptor-2."
Godiska R. , Chantry D. , Raport C.J. , Schweickart V.L. , Trong H.L. , Gray P.W.
J. Leukoc. Biol.61:353-360(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
6.

"Genomic organization, sequence analysis and transcriptional regulation of the human MCP-4 chemokine gene (SCYA13) in dermal fibroblasts: a comparison to other eosinophilic beta-chemokines."
Hein H. , Schluter C. , Kulke R. , Christophers E. , Schroeder J.-M. , Bartels J.
Biochem. Biophys. Res. Commun.255:470-476(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Skin fibroblast.
7.

"Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
Kalnine N. , Chen X. , Rolfs A. , Halleck A. , Hines L. , Eisenstein S. , Koundinya M. , Raphael J. , Moreira D. , Kelley T. , LaBaer J. , Lin Y. , Phelan M. , Farmer A.
Submitted (2003-05) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
8.

"Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
Ebert L. , Schick M. , Neubert P. , Schatten R. , Henze S. , Korn B.
Submitted (2004-05) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
9.

"DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage."
Zody M.C. , Garber M. , Adams D.J. , Sharpe T. , Harrow J. , Lupski J.R. , Nicholson C. , Searle S.M. , Wilming L. , Young S.K. , Abouelleil A. , Allen N.R. , Bi W. , Bloom T. , Borowsky M.L. , Bugalter B.E. , Butler J. , Chang J.L. , more...
Nature440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
10.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
11.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Brain.
12.

"Expression of a MCP-4 like novel CC-chemokine in human dermal fibroblasts: molecular cloning and RT-PCR analysis."
Bartels J.H. , Schlueter C. , Richter E. , Noso N. , Christophers E. , Schroeder J.-M.
Submitted (1996-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 17-95
tissue: Foreskin.
13.

"Structure of human monocyte chemoattractant protein 4 (MCP-4/CCL13)."
Barinka C. , Prahl A. , Lubkowski J.
Acta Crystallogr. D64:273-278(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.7 ANGSTROMS) OF 24-98;DISULFIDE BONDS

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